夏俊杰

夏俊杰

职称高级实验师

学科(专业):生理学

研究方向:器官移植免疫

邮箱xia@xmu.edu.cn

电话:0592-


教育背景:

2007.09–2012.07厦门大学医学院 生理学专业 博士(硕博连读)

工作经历:

2012.07–2015.07 厦门大学 器官移植研究所 实验师

2015.07–至今 厦门大学 器官移植研究所 高级实验师

主要研究领域:

器官移植免疫排斥机制的研究、免疫耐受的诱导以及基于干细胞技术和组织工程技术的器官与组织再生。

  

主要学术成果:

论文:

1

C. Gao#, J. Jiang#, P. Ma, P. Cheng, Y. Lian, B. Zhao, C. Li, Y. Peng, F. Wang, Y. Lin, N. Jin, J. Li, L. Wang, Q. Li, Y. Leng, J. Xia*, and Z. Qi*, “Arsenic Trioxide Induces T Cell Apoptosis and Prolongs Islet Allograft Survival in Mice,” Transplantation, vol. 99, pp. 1796–806, Sep. 2015.

2

P. P. Cheng#, X. C. Liu#, P. F. Ma, C. Gao, J. L. Li, Y. Y. Lin, W. Shao, S. Han, B. Zhao, L. M. Wang, J. Z. Fu, L. X. Meng, Q. Li, Q. Z. Lian*, J. J. Xia*, and Z. Q. Qi*, “iPSC-MSCs Combined with Low-Dose Rapamycin Induced Islet Allograft Tolerance Through Suppressing Th1 and Enhancing Regulatory T-Cell Differentiation,” Stem Cells Dev, vol. 24, pp. 1793–804, Aug. 2015.

3

C. Li#, T. Guan#, C. Gao, Y. Lin, G. Yan, M. Zhu, C. Lv, J. Xia*, and Z. Qi*, “Arsenic trioxide inhibits accelerated allograft rejection mediated by alloreactive CD8 memory T cells and prolongs allograft survival time,” Transpl Immunol, Jun. 2015.

4

W. Chen#, Y. Wu#, A. Shimizu, Y. Lian, M. Tasaki, V. Villani, S. Moran, J. Xia, K. Yamada, and Z. Qi*, “Rat-to-Chinese tree shrew heart transplantation is a novel small animal model to study non-Gal-mediated discordant xenograft humoral rejection,” Xenotransplantation, Nov. 2015.

5

Ma PF#, Jiang J#, Gao C, Cheng PP, Li JL, Huang X, Lin YY, Li Q, Peng YZ, Cai MC, Shao W, Zhu Q, Han S, Qin Q, Xia JJ*, Qi ZQ*. Immunosuppressive effect of compound K on islet transplantation in an STZ-induced diabetic mouse model. Diabetes. 2014;63(10):3458-69.

6

Cheng PP#, Xia JJ, Wang HL, Chen JB, Wang FY, Zhang Y, Huang X, Zhang QJ, Qi ZQ*. Islet transplantation reverses the effects of maternal diabetes on mouse oocytes. Reproduction. 2011;141(4):417-24.

7

Xia J#, Chen J, Shao W, Lan T, Wang Y, Xie B, Thorlacius H, Tian F, Huang R*, Qi Z*. Suppressing memory T cell activation induces islet allograft tolerance in alloantigen-primed mice. Transpl Int. 2010;23(11):1154-63.

8

Su Z#, Xia J#, Shao W, Cui Y, Tai S, Ekberg H, Corbascio M, Chen J*, Qi Z*. Small islets are essential for successful intraportal transplantation in a diabetes mouse model. Scand J Immunol. 2010;72(6):504-10.

9

F. Wang#, J. Xia#, J. Chen#, Y. Peng, P. Cheng, H. Ekberg, X. Wang, and Z. Qi*, “Combination of antibodies inhibits accelerated rejection mediated by memory T cells in xenoantigen-primed mice,” Xenotransplantation, vol. 17, pp. 460–8, Dec. 2010

10

Chen J#, Xia J, Axelsson B, Fritzson I, Ekberg H, Torngren M, Qi Z*. An N-(alkylcarbonyl)anthranilic acid derivative prolongs cardiac allograft survival synergistically with cyclosporine A in a high-responder rat model. Transpl Immunol. 2010;23(4):180-4.

主持课题:

1

福建省自然科学基金面上项目,新型异种心脏移植模型建立及机制研究,2016.04-2019.03

2

国家自然科学基金青年项目,MAPK信号通路在三氧化二砷抑制T细胞介导同种异体器官移植免疫排斥中的作用机制,2014.01-2016.12

3

厦门大学基础创新科研基金,MSCiPS辅助胰岛移植的应用及其机制研究,2011.07-2013.06